Jamisontown, New South Wales, Australia is located on the eastern side of the Nepean River, bounded on the south by the M4 Motorway, and the north by Jamison Road. York Road is the eastern boundary. Jamisontown is a diverse and changing suburb. A blend of residential, industrial and large retail outlets provide an atmosphere of a bustling and busy suburb of the Penrith Local Government area.

The upgraded and increasingly busy Mulgoa Road cuts through this suburb and takes travellers off the M4 Motorway to the Nepean River, Penrith Lakes Scheme, Penrith Panthers, Penrith Plaza and the city's Central Business District. Residents of Jamisontown are perfectly located to take full advantage of the facilities in their suburb and those close by.